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The detailed workflow is shown in Fig

During the procedure The IV is inserted into the vein through a small plastic butterfly vein catheter designed for comfort

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However, emerging evidence points to low ROS levels as a trigger for induction of autophagy [41]

In such metabolic scenario, CD8+ tumor-infiltrating cells have been characterized to be unable to efficiently uptake glucose and to have hyperpolarized, fragmented mitochondria generating large amounts of mROS, otherwise required for CD4+ T cell activation (51)