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This pocket is formed by residues in transmembrane helices 1 (TM1), 2 (TM2), 3 (TM3), and 7 (TM7), along with contributions from extracellular loop 2 (ECL2)

ICD-10 Code D53 Other Nutritional Anemias D53 includes nutritional anemias that do not fall under iron, B12, or folate deficiencies but still affect red blood cell production

A genomic mutational constraint map using variation in 76,156 human genomes

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NNMT and methionine restriction both reduced DNMT1 and DNMT3A expression, which may be another DNA hypomethylation mechanism (7)

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