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Hepatic effects that are considered adverse include death, abnormal clinical chemistry parameters, obvious functional organ impairment, DNA and mitochondrial alteration, glutathione depletion, hepatocyte necrosis, enhanced replicative DNA synthesis, generation of reactive oxygen species, and increased peroxisome proliferation (in rodents) (Williams and Iatropoulos 2002)

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The American Society of Clinical Oncology recommends AGAINST its use for preventing chemotherapy-related nerve damage [28][29]

It plays a vital role in energy production by transporting long-chain fatty acids into the mitochondria of your cells

Allen, Maternal Nutrient Metabolism and Requirements in Pregnancy and Lactation Dietary Guidelines for Americans Dietary Reference Intake (DRI) reports Office on Women's Health, US Department of Health and Human Services Nutrition Research Essential Fatty Acids What they do General Essential fatty acids are a type of polyunsaturated fatty acid (PUFA) that cannot be synthesized in the body and must come from the diet