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Sorafenib also targets branched-chain amino acid aminotransferase 2 by impairing its transcription and reducing the pool of intracellular glutamate, which reduces the activity of the xCT transporter [387]

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Synergistic therapeutic actions of antimicrobial peptides to treat multidrug-resistant bacterial infection

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Tumor CellIntrinsic p38 MAPK signaling promotes IL1-Mediated stromal inflammation and therapeutic resistance in pancreatic cancer [J]