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3.5 High mobility group box 1 and inflammatory signaling HMGB1, a nuclear protein, functions as a transcription factor and a DAMP that amplifies inflammatory responses (45)

F., Meijer, A

RNA sequencing analysis RNA (1 g) per sample was used for sequencing libraries generation by using KAPA mRNA HyperPrep Kit (KAPA Biosystems, Roche, Basel, Switzerland) following the manufacturers recommendations to remove ribosomal RNA

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Selenocysteine insertion sequence binding protein 2 (SBP2) binds to selenocysteine insertion sequence (SECIS) element which is located in the 3-untranslated region (3UTR) of selenoprotein mRNA, and mediates the transfer of Sec-tRNA [Ser]Sec to the A-site of ribosome which recognizes the UGA codon as the Sec integration codon

Destro et al., 2010)