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Oral B12 Supplements A common question is whether injections are necessary over high-dose oral supplements

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Jacob-Ferreira et al., 2013)

Reduced the dosage by no more than 0.5 mg every 3 days

Some contraindications (reasons not to take B12 shots) include: Allergies to cyanocobalamin or methylcobalamin Kidney or liver disease Eye issues, especially if you have Lebers disease A current infection If youre taking medication related to bone marrow You should talk to your doctor about the above conditions before getting B12 injections