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Melatonin and the CNS Individuals with neurodegenerative disorders (i.e., Alzheimers and Parkinsons disease, Huntingtons disease, autism) had significant flattened and attenuated melatonin rhythms compared to age-matched controls (37, 109)

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ELISA kits (R&D Systems, Abingdon, UK) for CCL3 (#DY270) and IL-1B (#DY201) were used and assays performed as per the manufacturers instructions

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10.2471/blt.07.034797 166 SereeE

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