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Funct Ecol 24:947949 Melov S, Schneider JA, Day BJ, Hinerfeld D, Coskun P, Mirra SS, Crapo JD, Wallace DC (1998) A novel neurological phenotype in mice lacking mitochondrial manganese superoxide dismutase

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NRF2 therefore accumulates and is free to translocate to the nucleus through the nuclear pore complex (NPC)

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In addition to directly acting on methionine availability, the transporters, metabolic enzymes, and sensors of methionine represent potential targets for therapeutic intervention
