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S.MilesL.ReaumeJ.et al (2011)

If the inflammation results in collagen destruction, theres a loss of skin tissue that leads to pitting or indentations in the skin, called atrophic scars

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Add directly to culture medium at final concentrations of 0.110 mM, depending on assay sensitivity

History [edit] Descriptions of deficiency effects [edit] Between 1849 and 1887, Thomas Addison described a case of pernicious anemia, William Osler and William Gardner first described a case of neuropathy, Hayem described large red cells in the peripheral blood in this condition, which he called "giant blood corpuscles" (now called macrocytes), Paul Ehrlich identified megaloblasts in the bone marrow, and Ludwig Lichtheim described a case of myelopathy